Regulome Explorer Tools

Regulome Explorer facilitates the integrative exploration of associations in clinical and molecular TCGA data

Final Releases

CRC Aggressiveness Explorer
Combined p-value approach to identifying significant features in terms of tumor aggressiveness

This analysis is part of a study of human colon and rectal cancer published in Comprehensive molecular characterization of human colon and rectal cancer which was performed by The Cancer Genome Atlas Research Network. Nature 487, 330-337 (2012) .

Beta Releases

All Pairs Significance Tests
Identification of significant heterogeneous feature associations via standard statistical tests
Random Forest Analysis
Multi-variate, non-linear associations of heterogeneous features
Pubcrawl
Literature-derived cross-validation and interpretation of feature association

Find out more about this and other software at CSACR.

Regulome Explorer is an effort by the Center for Systems Analysis of the Cancer Regulome (CSACR), a collaboration between the Institute for Systems Biology and The University of Texas MD Anderson Cancer Center. CSACR is a Genome Data Analysis Center within The Cancer Genome Atlas project. The Principal Investigators at CSACR are Ilya Shmulevich (ISB) and Wei Zhang (MDACC).

The project described was supported by Award Number U24CA143835 from the National Cancer Institute. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Cancer Institute or the National Institutes of Health.